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Using ClinVar to Share Germline and Somatic Variant Classifications from Clinical Genomic Testing for Cancer
12/17/2024
1:00 PM - 2:00 PM Eastern

Event Description

Clinical genetics testing laboratories have benefited from sharing variant classifications of germline variants for monogenic disorders with ClinVar since its introduction in 2013. In January 2024, ClinVar was updated to accept classifications of somatic variants for cancer, including assertions of oncogenicity and clinical impact. This webinar will describe how genetic testing laboratories have benefited from sharing germline variants through ClinVar, and how cancer testing laboratories can take advantage of sharing classifications of somatic variants. 

Speakers: Melissa J. Landrum PhD and Sharon E. Plon MD, PhD


Level of Instruction: Intermediate 

Learning Objectives: At the end of this session, the participant will be able to:

1. Discuss the benefits of sharing variant classifications in public databases
2. Describe the types of data that can be submitted to ClinVar for somatic variants
3. Summarize the methods to submit data to ClinVar